initial analysis used mascot protein identification software Search Results


western blot analysis  (Sino Biological)
94
Sino Biological western blot analysis
Western Blot Analysis, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mascot database search  (Matrix Science)
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Matrix Science mascot database search
Mascot Database Search, supplied by Matrix Science, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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corona proteins  (PChem Associates Inc)
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PChem Associates Inc corona proteins
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lysc lysyl endopeptidase mass spectrometry grade  (FUJIFILM)
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FUJIFILM lysc lysyl endopeptidase mass spectrometry grade
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2d imaging analysis software  (PHORETIX INTERNATIONAL LIMITED)
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PHORETIX INTERNATIONAL LIMITED 2d imaging analysis software
2d Imaging Analysis Software, supplied by PHORETIX INTERNATIONAL LIMITED, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mascot analysis  (Matrix Science)
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Matrix Science mascot analysis
Mascot Analysis, supplied by Matrix Science, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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protein spots  (Bio-Rad)
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Bio-Rad protein spots
Protein Spots, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mascot probability analysis  (Matrix Science)
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Matrix Science mascot probability analysis
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genecards database  (Human Protein Atlas)
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Human Protein Atlas genecards database
Tissue-based expression profile of PON1. Expression levels are measured in parts per million (PPM), indicating tissue-specific functional relevance <t>(GeneCards).</t>
Genecards Database, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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somascan protein array  (SomaLogic)
90
SomaLogic somascan protein array
Analysis of circulating EVs proteome by <t>SOMAScan</t> protein array in all three cohorts. (A) Venn diagram of differentially expressed EV proteins in patients with precirrhotic NASH versus healthy controls or patients with cirrhotic NASH. (B) Venn diagram of differentially expressed EV proteins in patients with cirrhotic NASH compared with healthy controls or patients with precirrhotic NASH. A cutoff of adjusted P value of 0.01 was used for both Venn diagrams. (C) Unsupervised hierarchical clustering analysis of the top 50 differentially expressed circulating EV proteins in patients with cirrhotic NASH versus patients with precirrhotic NASH versus healthy controls (n = 7/group). The top 50 proteins listed on the heat map were selected based on the adjusted P value of 0.05 from the cirrhotic NASH versus healthy controls comparison. Mean and SD of all three groups were used to normalize the expression value. The closer the color is to bright blue, the lower the expression, whereas the closer the color is to bright red, the higher the expression.
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initial analysis used mascot protein identification software  (Matrix Science)
86
Matrix Science initial analysis used mascot protein identification software
Analysis of circulating EVs proteome by <t>SOMAScan</t> protein array in all three cohorts. (A) Venn diagram of differentially expressed EV proteins in patients with precirrhotic NASH versus healthy controls or patients with cirrhotic NASH. (B) Venn diagram of differentially expressed EV proteins in patients with cirrhotic NASH compared with healthy controls or patients with precirrhotic NASH. A cutoff of adjusted P value of 0.01 was used for both Venn diagrams. (C) Unsupervised hierarchical clustering analysis of the top 50 differentially expressed circulating EV proteins in patients with cirrhotic NASH versus patients with precirrhotic NASH versus healthy controls (n = 7/group). The top 50 proteins listed on the heat map were selected based on the adjusted P value of 0.05 from the cirrhotic NASH versus healthy controls comparison. Mean and SD of all three groups were used to normalize the expression value. The closer the color is to bright blue, the lower the expression, whereas the closer the color is to bright red, the higher the expression.
Initial Analysis Used Mascot Protein Identification Software, supplied by Matrix Science, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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tridex protein analyser  (IDEX)
90
IDEX tridex protein analyser
Analysis of circulating EVs proteome by <t>SOMAScan</t> protein array in all three cohorts. (A) Venn diagram of differentially expressed EV proteins in patients with precirrhotic NASH versus healthy controls or patients with cirrhotic NASH. (B) Venn diagram of differentially expressed EV proteins in patients with cirrhotic NASH compared with healthy controls or patients with precirrhotic NASH. A cutoff of adjusted P value of 0.01 was used for both Venn diagrams. (C) Unsupervised hierarchical clustering analysis of the top 50 differentially expressed circulating EV proteins in patients with cirrhotic NASH versus patients with precirrhotic NASH versus healthy controls (n = 7/group). The top 50 proteins listed on the heat map were selected based on the adjusted P value of 0.05 from the cirrhotic NASH versus healthy controls comparison. Mean and SD of all three groups were used to normalize the expression value. The closer the color is to bright blue, the lower the expression, whereas the closer the color is to bright red, the higher the expression.
Tridex Protein Analyser, supplied by IDEX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Tissue-based expression profile of PON1. Expression levels are measured in parts per million (PPM), indicating tissue-specific functional relevance (GeneCards).

Journal: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research

Article Title: Periodontal Implications of Porphyromonas gingivalis -Derived Metabolites in Host Antioxidant and Anti-Inflammatory Mechanisms: A Computational Analysis

doi: 10.12659/MSM.949167

Figure Lengend Snippet: Tissue-based expression profile of PON1. Expression levels are measured in parts per million (PPM), indicating tissue-specific functional relevance (GeneCards).

Article Snippet: Initial analysis using the GeneCards database, which integrates data from sources such as GTEx and the Human Protein Atlas (HPA), revealed high PON1 expression in blood plasma and serum, elevated levels in monocytes and synovial fluid, and moderate expression in the oral epithelium and salivary glands.

Techniques: Expressing, Functional Assay

Analysis of circulating EVs proteome by SOMAScan protein array in all three cohorts. (A) Venn diagram of differentially expressed EV proteins in patients with precirrhotic NASH versus healthy controls or patients with cirrhotic NASH. (B) Venn diagram of differentially expressed EV proteins in patients with cirrhotic NASH compared with healthy controls or patients with precirrhotic NASH. A cutoff of adjusted P value of 0.01 was used for both Venn diagrams. (C) Unsupervised hierarchical clustering analysis of the top 50 differentially expressed circulating EV proteins in patients with cirrhotic NASH versus patients with precirrhotic NASH versus healthy controls (n = 7/group). The top 50 proteins listed on the heat map were selected based on the adjusted P value of 0.05 from the cirrhotic NASH versus healthy controls comparison. Mean and SD of all three groups were used to normalize the expression value. The closer the color is to bright blue, the lower the expression, whereas the closer the color is to bright red, the higher the expression.

Journal: Hepatology Communications

Article Title: Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH

doi: 10.1002/hep4.1556

Figure Lengend Snippet: Analysis of circulating EVs proteome by SOMAScan protein array in all three cohorts. (A) Venn diagram of differentially expressed EV proteins in patients with precirrhotic NASH versus healthy controls or patients with cirrhotic NASH. (B) Venn diagram of differentially expressed EV proteins in patients with cirrhotic NASH compared with healthy controls or patients with precirrhotic NASH. A cutoff of adjusted P value of 0.01 was used for both Venn diagrams. (C) Unsupervised hierarchical clustering analysis of the top 50 differentially expressed circulating EV proteins in patients with cirrhotic NASH versus patients with precirrhotic NASH versus healthy controls (n = 7/group). The top 50 proteins listed on the heat map were selected based on the adjusted P value of 0.05 from the cirrhotic NASH versus healthy controls comparison. Mean and SD of all three groups were used to normalize the expression value. The closer the color is to bright blue, the lower the expression, whereas the closer the color is to bright red, the higher the expression.

Article Snippet: Lysates of purified circulating EVs isolated from seven randomly selected healthy control, precirrhotic NASH, and cirrhotic NASH samples were used for an initial discovery study using the SOMAscan protein array (SomaLogic, Boulder, CO), which included 1,345 unique proteins.

Techniques: Protein Array, Comparison, Expressing